Princeton S. S. Wilks Memorial Lecture Series will feature one speaker per year.

This lecture series is funded by the S. S. Wilks Memorial Fund endowed in honor of the late Princeton Professor of Statistics Samuel Stanley Wilks.

#### Three principles of data science: predictability, stability, and computability

by Bin Yu (UC Berkeley)

**Monday, March 26 at 5:00pm**

Computer Science 104

Abstract: In this talk, I'd like to discuss the intertwining importance and connections of three principles of data science in the title. They will be demonstrated in the context of two collaborative projects in neuroscience and genomics, respectively. The first project in neuroscience uses transfer learning to integrate fitted convolutional neural networks (CNNs) on ImageNet with regression methods to provide predictive and stable characterizations of neurons from the challenging primary visual cortex V4. The second project proposes iterative random forests (iRF) as a stablized RF to seek predictable and interpretable high-order interactions between biomolecules.

Bin Yu is Chancellor’s Professor in the Departments of Statistics and of Electrical Engineering & Computer Science at the University of California at Berkeley and a former Chair of Statistics at Berkeley. She is founding co-director of the Microsoft Joint Lab at Peking University on Statistics and Information Technology. Her group at Berkeley is engaged in interdisciplinary research with scientists from genomics, neuroscience, and medicine. In order to solve data problems in these domain areas, her group employs quantitative critical thinking and develops statistical and machine learning algorithms and theory. She has published more than 100 scientific papers in premier journals in statistics, machine learning, information theory, signal processing, remote sensing, neuroscience, genomics, and networks.
She is a member of the U.S. National Academy of Sciences and fellow of the American Academy of Arts and Sciences. She was a Guggenheim Fellow in 2006, an invited speaker at ICIAM in 2011, the Tukey Memorial Lecturer of the Bernoulli Society in 2012, and an invited speaker at the Rietz Lecture of Institute of Mathematical Statistics (IMS) in 2016. She was IMS president in 2013–2014, and she is a fellow of IMS, ASA, AAAS, and IEEE. She has served or is serving on leadership committees of NAS-BMSA, SAMSI, IPAM, and ICERM and on editorial boards for the Journal of Machine Learning, Annals of Statistics, and Annual Review of Statistics. |